Description

1-Cbz-4,4-Dimethyl-Pyrrolidine-3-Carboxylic Acid is a high-purity, protected amino acid derivative featuring a carboxybenzyl (Cbz) protecting group on the nitrogen and a carboxylic acid moiety. This compound serves as a critical building block in modern organic synthesis, particularly for the controlled construction of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptides, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid analog for the solid-phase or solution-phase synthesis of modified peptides and peptidomimetics.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Chemical Biology: Useful as a probe or linker precursor in the synthesis of bioconjugates and chemical tools.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Academic Research: Applied in methodological development and synthetic organic chemistry studies within university laboratories.

Basic Information

Product Name	1-Cbz-4,4-Dimethyl-Pyrrolidine-3-Carboxylic Acid
CAS No.	2089381-17-7
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4,4-dimethylpyrrolidine-3-carboxylic acid; 4,4-Dimethyl-1-[(phenylmethoxy)carbonyl]-3-pyrrolidinecarboxylic acid; 3-Pyrrolidinecarboxylic acid, 4,4-dimethyl-1-[(phenylmethoxy)carbonyl]-; 1-Carbobenzoxy-4,4-dimethyl-3-pyrrolidinecarboxylic acid; 1-Cbz-4,4-dimethyl-3-pyrrolidinecarboxylic acid; N-Cbz-4,4-dimethyl-3-pyrrolidinecarboxylic acid; N-Carbobenzyloxy-4,4-dimethylpyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Cbz-4,4-Dimethyl-Pyrrolidine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.