Description

Ethyl (1S,2S)-Rel-2-(4-Ethoxy-3-Fluorophenyl)Cyclopropane-1-Carboxylate is a high-purity chiral cyclopropane derivative, a crucial building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which enable the precise construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety and fluorinated aromatic ring contribute to biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the study and development of new stereoselective catalytic reactions.
• Material Science Precursor: Potential building block for specialty polymers or liquid crystals, leveraging its rigid cyclopropane structure and aromatic functionality.
• Chemical Biology Probe Development: Utilized in the synthesis of molecular probes for studying enzyme mechanisms or biological pathways due to its modifiable ester group and fluorinated label.

Basic Information

Product Name	Ethyl (1S,2S)-Rel-2-(4-Ethoxy-3-Fluorophenyl)Cyclopropane-1-Carboxylate
CAS No.	2055840-77-0
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	Ethyl (1S,2S)-2-(4-Ethoxy-3-fluorophenyl)cyclopropanecarboxylate; (1S,2S)-Ethyl 2-(4-Ethoxy-3-fluorophenyl)cyclopropanecarboxylate; rel-(1S,2S)-Ethyl 2-(4-Ethoxy-3-fluorophenyl)cyclopropanecarboxylate; Ethyl (1S,2S)-2-(3-Fluoro-4-ethoxyphenyl)cyclopropanecarboxylate; (1S,2S)-2-(4-Ethoxy-3-fluorophenyl)cyclopropanecarboxylic Acid Ethyl Ester; Fused Cyclopropane Ester Intermediate; Chiral Fluorinated Cyclopropane Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with specifications tailored for research and process development use. Certificates of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.