Description

4-Chloro-2,5-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially in creating biaryl structures common in many therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific halogenated aryl motifs.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as those for OLEDs and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex organic molecules.
• Custom Synthesis: Provides a critical handle for contract research and manufacturing organizations (CROs/CMOs) to build bespoke compounds for clients.

Basic Information

Product Name	4-Chloro-2,5-Difluorophenylboronic Acid
CAS No.	2055778-26-0
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(4-Chloro-2,5-difluorophenyl)boronic Acid; 4-Chloro-2,5-difluorobenzeneboronic Acid; 2,5-Difluoro-4-chlorophenylboronic Acid; Boronic acid, B-(4-chloro-2,5-difluorophenyl)-; CAS 2055778-26-0
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.