Description

Carboxyrhodamine 110-Peg4- Alkyne is a high-purity, multifunctional fluorescent probe designed for advanced bioconjugation and labeling applications. This compound matters for researchers and developers requiring precise, click chemistry-compatible tags for biomolecules, enabling sensitive detection and imaging. It is primarily needed by professionals in pharmaceutical R&D, diagnostic assay development, and life science research for applications in flow cytometry, fluorescence microscopy, and bioanalytical method development.

Application

• Bioconjugation via Click Chemistry: Utilizes the alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to label azide-modified biomolecules like proteins, antibodies, and oligonucleotides.
• Fluorescent Labeling for Bioimaging: Serves as a bright, green-fluorescent tag for intracellular and in vitro imaging in fluorescence microscopy and confocal imaging studies.
• Flow Cytometry & Cell Sorting: Used to label cell surface markers or intracellular targets for analysis and isolation of specific cell populations.
• Diagnostic Assay Development: Acts as a critical component in developing fluorescent immunoassays (FLISA) and other diagnostic tests requiring high-sensitivity detection.
• Protein & Peptide Tracking: Enables the study of protein localization, interaction, and turnover in live or fixed cells.
• Nucleic Acid Probes: Can be conjugated to nucleic acids for fluorescence in situ hybridization (FISH) and real-time PCR detection applications.
• Drug Delivery & Targeting Research: Incorporated into drug delivery systems (e.g., antibody-drug conjugates, nanoparticles) to track distribution and uptake.
• Material Science & Surface Modification: Used to functionalize surfaces and materials with fluorescent properties for sensor development and biointerface studies.

Basic Information

Product Name	Carboxyrhodamine 110-Peg4- Alkyne
CAS No.	2055103-66-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5/6-Carboxy-X-rhodamine 110-PEG4-Alkyne; CR110-PEG4-Alkyne; 5(6)-Carboxyrhodamine 110 tetraethyleneglycol alkyne; Rhodamine 110 derivative PEG4 alkyne; Fluorescent PEG linker alkyne; Click chemistry fluorescent probe; Green fluorescent alkyne dye; Polyethylene glycol tethered rhodamine alkyne
EINECS	Contact for details

Quality Control

Our Carboxyrhodamine 110-Peg4- Alkyne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for sensitive research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions for long-term stability. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	Red to purple solid or powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~500 nm
Emission Maximum	~525 nm
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.