Description

Propargyl-Peg10-Alcohol is a specialized bifunctional polyethylene glycol derivative featuring a terminal propargyl group and a hydroxyl group. This unique structure makes it a highly versatile intermediate for click chemistry, bioconjugation, and polymer synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity building blocks for creating complex molecular architectures.

Application

• Bioconjugation and Linker Chemistry: Acts as a hydrophilic spacer arm for attaching drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Polymer and Dendrimer Synthesis: Serves as a key monomer or initiator for creating functionalized PEG-based polymers, hydrogels, and dendritic structures with tailored properties.
• Pharmaceutical Development: Used in the synthesis of prodrugs and drug delivery systems to improve solubility, bioavailability, and pharmacokinetic profiles of active pharmaceutical ingredients (APIs).
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes where stable, water-soluble linkers are required.
• Surface Modification: Facilitates the functionalization of surfaces (e.g., gold, silica) with PEG brushes to create non-fouling, biocompatible coatings.
• Material Science: Integral in the development of smart materials, self-assembled monolayers (SAMs), and responsive gels.

Basic Information

Item	Detail
Product Name	Propargyl-Peg10-Alcohol
CAS No.	2055022-35-8
Molecular Formula	C25H48O12
Molecular Weight	540.65 g/mol
Synonyms	Propargyl-PEG10-OH; 2,5,8,11,14,17,20,23,26,29-Decaoxahentriacont-30-yn-1-ol; mPEG10-Propargyl; α-Propargyl-ω-hydroxy-decaethylene glycol; Propargyl terminated PEG10 alcohol; Propargyl-PEG10; Alkyne-PEG10-OH; 30-Hydroxy-2,5,8,11,14,17,20,23,26,29-decaoxahentriacont-30-yne
EINECS	Contact for details

Quality Control

Our Propargyl-Peg10-Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial applications. A Certificate of Analysis (COA) detailing purity, identity, and key specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight (GPC)	540 ± 20 g/mol
Functional Group Assay	≥ 90% (OH & Alkyne)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.