Description

tert-Butyl (1-(Pyrimidin-5-Yl)Cyclopropyl)Carbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl (1-(Pyrimidin-5-Yl)Cyclopropyl)Carbamate
CAS No.	2054952-80-4
Molecular Formula	C12H17N3O2
Molecular Weight	235.29 g/mol
Synonyms	Boc-1-(Pyrimidin-5-yl)cyclopropylamine; 1-(Pyrimidin-5-yl)cyclopropanamine, N-Boc-protected; tert-Butyl N-[1-(pyrimidin-5-yl)cyclopropyl]carbamate; 1-(Pyrimidin-5-yl)cyclopropylcarbamic acid tert-butyl ester; 5-(1-((tert-Butoxycarbonyl)amino)cyclopropyl)pyrimidine; (1-(Pyrimidin-5-yl)cyclopropyl)carbamic acid tert-butyl ester; N-Boc-1-(5-pyrimidinyl)cyclopropanamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-(Pyrimidin-5-Yl)Cyclopropyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.