Description

3,5-Dichloro-2-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those requiring halogenated, fluorinated aromatic scaffolds.
• Agrochemical Compound Development: Serves as a building block for synthesizing novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Biology & Probe Development: Useful for creating tagged molecules and biochemical probes for diagnostic and research purposes.
• Scale-up and Process Chemistry: Suitable for optimization and pilot-scale synthesis in process development for commercial manufacturing.

Basic Information

Product Name	3,5-Dichloro-2-Fluorophenylboronic Acid
CAS No.	2048237-95-0
Molecular Formula	C6H4BCl2FO2
Molecular Weight	208.82 g/mol
Synonyms	(3,5-Dichloro-2-fluorophenyl)boronic acid; 2-Fluoro-3,5-dichlorophenylboronic acid; Boronic acid, B-(3,5-dichloro-2-fluorophenyl)-; 3,5-Dichloro-2-fluorobenzeneboronic acid; (2-Fluoro-3,5-dichlorophenyl)boronic acid; 2048237-95-0; B-(3,5-Dichloro-2-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.