Description

L-Norvaline, 5-(Methylthio)-n-[(Phenylmethoxy)Carbonyl]- is a specialized, non-proteinogenic amino acid derivative featuring a unique side-chain modification. This compound is a critical building block in advanced pharmaceutical research and peptide synthesis, offering precise structural control for developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating peptide-based drugs, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based pharmaceuticals and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified norvaline residues, influencing peptide conformation and bioactivity.
• Biochemical Research: Serves as a substrate analog or inhibitor in enzymatic studies to investigate metabolic pathways and enzyme mechanisms.
• Ligand Development: Employed in the design and synthesis of specialized ligands for catalysis or molecular recognition applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-Norvaline, 5-(Methylthio)-n-[(Phenylmethoxy)Carbonyl]-
CAS No.	2044704-55-2
Molecular Formula	C14H19NO4S
Molecular Weight	297.37 g/mol
Synonyms	N-Cbz-5-(Methylthio)-L-norvaline; (S)-2-(((Benzyloxy)carbonyl)amino)-5-(methylthio)pentanoic acid; Z-5-(Methylthio)-L-norvaline; N-[(Benzyloxy)carbonyl]-5-(methylthio)-L-norvaline; N-Carbobenzoxy-5-(methylthio)-L-norvaline; 5-(Methylmercapto)-N-carbobenzyloxy-L-norvaline; Nα-Cbz-S-methyl-L-homocysteine
EINECS	Contact for details

Quality Control

Our L-Norvaline, 5-(Methylthio)-n-[(Phenylmethoxy)Carbonyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.