Description

Nintedanib-013-Ze CAS NO 2036139-30-5 is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of targeted therapeutic agents, particularly in the field of oncology. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Oncology Research: Used in preclinical and discovery research for developing tyrosine kinase inhibitors and other targeted cancer therapies.
• Process Chemistry & Scale-Up: Serves as a critical reagent for process optimization and pilot-scale manufacturing of complex molecules.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and medicinal chemistry.
• Custom Synthesis: A starting material for the custom synthesis of specialized derivatives and analogs for proprietary research programs.

Basic Information

Product Name	Nintedanib-013-Ze
CAS No.	2036139-30-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Nintedanib Impurity 13; Nintedanib Related Compound Z; Nintedanib-013; 2036139-30-5; Nintedanib Intermediate Ze; BIBF 1120 Impurity 13; Nintedanib Derivative-013; Nintedanib Analog Ze
EINECS	Contact for details

Quality Control

Our Nintedanib-013-Ze is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with ICH guidelines and cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.