Description

2-Chloro-6-(Trifluoromethoxy)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated and fluorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structural properties can influence charge transport.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CROs serving the global life sciences market.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	2036084-49-6
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.37 g/mol
Synonyms	[2-Chloro-6-(trifluoromethoxy)phenyl]boronic acid; (2-Chloro-6-(trifluoromethoxy)phenyl)boronic acid; 2-Chloro-6-(trifluoromethoxy)benzeneboronic acid; Boronic acid, B-[2-chloro-6-(trifluoromethoxy)phenyl]-; 2-Chloro-6-trifluoromethoxyphenylboronic Acid; 2-Chloro-α,α,α-trifluoro-p-anisylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.