Description

3-Chloro-2,6-Difluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound matters as a critical building block in modern cross-coupling reactions, enabling the precise construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key intermediate for creating biaryl and heterobiaryl structures central to drug discovery programs.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Synthesis: Facilitates the introduction of the substituted difluorophenyl moiety into complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): A standard reagent for custom synthesis and scale-up services.

Basic Information

Product Name	3-Chloro-2,6-Difluorophenylboronic Acid Pinacol Ester
CAS No.	2028305-90-8
Molecular Formula	C₁₂H₁₄BClF₂O₂
Molecular Weight	274.50 g/mol
Synonyms	(3-Chloro-2,6-difluorophenyl)boronic acid pinacol ester; 2-(3-Chloro-2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-2,6-difluorophenylboronic Acid Neopentyl Glycol Ester (common alternative); 3-Chloro-2,6-difluorophenyl-Bpin; Boronic acid, B-(3-chloro-2,6-difluorophenyl)-, 1,1-dimethylethyl ester; CAS 2028305-90-8; Pinacol (3-chloro-2,6-difluorophenyl)boronate
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.