Description

Tau Peptide (323-335) is a synthetic peptide fragment corresponding to amino acid residues 323-335 of the human tau protein. This sequence-specific peptide is a critical research tool for studying tau protein function, aggregation, and its role in neurodegenerative pathologies. It is primarily utilized by researchers and developers in the fields of neuroscience, biochemistry, and pharmaceutical discovery, particularly for antibody development, epitope mapping, and in vitro diagnostic assay design.

Application

• Biomedical Research: Fundamental studies on tau protein structure, function, and post-translational modifications.
• Antibody Production & Characterization: Serves as a key antigen for generating and screening sequence-specific monoclonal or polyclonal antibodies.
• Diagnostic Assay Development: Used as a coating antigen or standard in ELISA and other immunoassays for detecting tau-related biomarkers.
• Neurodegenerative Disease Modeling: Investigation of tau aggregation mechanisms relevant to Alzheimer's disease and other tauopathies.
• Drug Discovery Screening: Target peptide for high-throughput screening of compounds designed to inhibit abnormal tau interactions or aggregation.
• Quality Control Reference: Acts as a reference standard for the quality control of tau protein preparations or related diagnostic kits.

Basic Information

Product Name	Tau Peptide (323-335)
CAS No.	2022956-59-6
Molecular Formula	C65H108N20O21S
Molecular Weight	1529.7 g/mol
Synonyms	Tau (323-335) peptide; Human tau protein fragment 323-335; Tau peptide residues 323-335; H-Tyr-Lys-Thr-Ile-Ala-Val-Gly-Asp-Thr-Val-Lys-Glu-OH; Anti-tau antibody epitope peptide; Microtubule-associated protein tau (323-335); MAPT (323-335); Tau aggregation-related peptide.
EINECS	Contact for details

Quality Control

Our Tau Peptide (323-335) is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, essential for reliable research outcomes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, amino acid analysis, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.