Description

Tau Peptide (1-16) CAS NO 2022956-53-0 is a synthetic peptide fragment corresponding to the first 16 amino acids of the human tau protein. This sequence is critical for research into tau protein structure, function, and its role in neurodegenerative pathologies. It serves as an essential biochemical tool for scientists and pharmaceutical developers focused on Alzheimer's disease and related tauopathies. The peptide is supplied as a high-purity, lyophilized solid for reliable and reproducible experimental results.

Application

• Neuroscience Research: Fundamental studies on tau protein biochemistry, aggregation mechanisms, and microtubule binding dynamics.
• Drug Discovery & Screening: Used as a target or reference standard in high-throughput assays to identify potential therapeutic compounds that modulate tau interaction or aggregation.
• Antibody Development & Epitope Mapping: Serves as a key antigen for generating and characterizing antibodies specific to the N-terminal region of the tau protein.
• Diagnostic Assay Development: Utilized in the calibration and validation of immunoassays (e.g., ELISA) designed to detect tau or its fragments in biological samples.
• Biomarker Studies: Investigation of tau proteolysis and the generation of specific fragments as potential biomarkers for neurological disease progression.
• Academic & Institutional Research: A standard reagent for university and research institute labs studying cytoskeletal proteins and neurodegeneration.

Basic Information

Product Name	Tau Peptide (1-16)
CAS No.	2022956-53-0
Molecular Formula	C79H130N24O25S
Molecular Weight	1848.1 g/mol
Synonyms	Tau (1-16) peptide; Human tau protein fragment 1-16; MAPT (1-16); Microtubule-associated protein tau (1-16); N-terminal tau peptide; Ac-MDAGTMDHDSGLSQDC-NH2 (disulfide bridge: Cys2-Cys15); Tau-derived peptide; Neurofibrillary tangle research peptide
EINECS	Contact for details

Quality Control

Every batch of Tau Peptide (1-16) is manufactured and analyzed under strict quality management protocols. We guarantee high purity and batch-to-batch consistency through comprehensive analytical testing, including reversed-phase HPLC and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity, and content data is supplied with each product to ensure it meets your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.