Description

H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-Oh is a synthetic peptide sequence of significant interest in advanced biochemical research and development. This compound serves as a critical building block for studying protein-protein interactions, enzyme specificity, and as a potential precursor for novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in peptide synthesis, medicinal chemistry, and proteomics. The precise sequence offers a valuable tool for investigating biological pathways and developing targeted bioactive molecules.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based drug candidates and investigational new drugs (INDs).
• Biochemical Assay Development: Used as a standard or substrate in enzymatic assays to study protease activity and specificity.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Proteomics and Biomarker Discovery: Employed in mass spectrometry and other analytical techniques for method development and calibration.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cell signaling, molecular biology, and peptide science.
• Custom Peptide Synthesis: Acts as a starting material or fragment for the custom synthesis of longer, more complex peptide chains for client-specific projects.

Basic Information

Product Name	H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-Oh
CAS No.	2022956-41-6
Molecular Formula	C41H68N16O15S
Molecular Weight	1049.14 g/mol
Synonyms	TPNQRQNVC-OH; H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH; Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys; TPNQRQNVC Peptide; L-Threonyl-L-prolyl-L-asparaginyl-L-glutaminyl-L-arginyl-L-glutaminyl-L-asparaginyl-L-valyl-L-cysteine; Peptide Sequence TPNQRQNVC; Custom Peptide 2022956-41-6
EINECS	Contact for details

Quality Control

Our H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.