Description

2-(3-Oxocyclobutyl)Acetonitrile is a versatile and high-purity chemical intermediate featuring a reactive cyclobutanone moiety linked to an acetonitrile group. This compound is valued for its unique structural framework, enabling its use in advanced synthetic pathways, particularly in pharmaceutical research and fine chemical manufacturing. It serves as a critical building block for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex, functionalized molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing strained ring systems for targeted drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and specialty materials.
• Organic Synthesis Building Block: Employed in cycloaddition reactions, ring-expansion strategies, and the construction of complex natural product analogs.
• Ligand and Catalyst Development: Useful for creating novel chelating ligands or organocatalysts in asymmetric synthesis.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-(3-Oxocyclobutyl)Acetonitrile
CAS No.	2007916-61-0
Molecular Formula	C6H7NO
Molecular Weight	109.13 g/mol
Synonyms	3-Oxocyclobutaneacetonitrile; 2-(3-Oxocyclobutyl)ethanenitrile; Cyclobutanone, 2-cyanoethyl-; 3-Oxocyclobutylacetonitrile; (3-Oxocyclobutyl)acetonitrile; 2-(3-Oxocyclobutyl)acetonitrile; 2007916-61-0; 3-Cyclobutanoneacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(3-Oxocyclobutyl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.