Description

8-Bromo-5-Fluoro-2,2-Dimethyl-Benzo[1,3]Dioxin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzodioxinone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce the bromo-fluoro benzodioxinone moiety into more complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides, leveraging its halogenated heterocyclic core.
• Material Science: Investigated for the creation of specialty polymers and organic electronic materials due to its fused ring system and halogen substituents.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	8-Bromo-5-Fluoro-2,2-Dimethyl-Benzo[1,3]Dioxin-4-One
CAS No.	2006317-76-4
Molecular Formula	C10H7BrFO3
Molecular Weight	273.06 g/mol
Synonyms	8-Bromo-5-fluoro-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one; 2,2-Dimethyl-8-bromo-5-fluorobenzo[1,3]dioxin-4-one; 8-Bromo-5-fluoro-2,2-dimethyl-1,3-benzodioxin-4-one; 2006317-76-4; Benzo[1,3]dioxin-4-one, 8-bromo-5-fluoro-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoro-2,2-Dimethyl-Benzo[1,3]Dioxin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.