Description

n-Benzyl-n-{2-[Benzyl(Trifluoroacetyl)Amino]Ethyl}-2,2,2-Trifluoroacetamide is a specialized trifluoroacetylated amine derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development where its unique fluorine-containing groups can impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as peptide mimetics, catalyst ligands, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Peptidomimetics & PROTACs: Serves as a critical component in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation therapies.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: An essential reagent for introducing trifluoroacetyl protecting groups or fluorinated motifs into complex organic molecules.
• Material Science: Investigated for use in the synthesis of specialty polymers and advanced materials with unique surface properties.

Basic Information

Item	Detail
Product Name	n-Benzyl-n-{2-[Benzyl(Trifluoroacetyl)Amino]Ethyl}-2,2,2-Trifluoroacetamide
CAS No.	299929-95-6
Molecular Formula	C20H18F6N2O2
Molecular Weight	432.36 g/mol
Synonyms	N,N'-Dibenzyl-N,N'-bis(trifluoroacetyl)ethylenediamine; 1,2-Bis[N-benzyl-N-(trifluoroacetyl)amino]ethane; N1,N2-Dibenzyl-N1,N2-bis(2,2,2-trifluoroacetyl)ethane-1,2-diamine; BTFAA-DBEDA; N,N'-Dibenzylethylenediamine N,N'-bis(trifluoroacetamide); Ethylenediamine, N,N'-dibenzyl-, N,N'-bis(trifluoroacetyl)-; Bis(trifluoroacetyl) derivative of N,N'-dibenzylethylenediamine
EINECS	Contact for details

Quality Control

Our n-Benzyl-n-{2-[Benzyl(Trifluoroacetyl)Amino]Ethyl}-2,2,2-Trifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic data are provided and available upon request. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.