Description

n-(4-Aminophenyl)Cyclobutanecarboxamide is a specialized organic compound featuring a cyclobutane ring linked to an aniline derivative, serving as a key building block in advanced chemical synthesis. This compound is valued for its unique structural motif, which is crucial for imparting specific steric and electronic properties in target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators, leveraging its bicyclic structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing complex molecular architectures via amide coupling or further functionalization of the aromatic amine group.
• Bioconjugation Chemistry: The reactive amino group enables its use in linking pharmacophores or creating antibody-drug conjugates (ADCs) for targeted therapies.

Basic Information

Product Name	n-(4-Aminophenyl)Cyclobutanecarboxamide
CAS No.	299440-37-2
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	4-Aminophenyl cyclobutanecarboxamide; Cyclobutanecarboxamide, N-(4-aminophenyl)-; N-(4-Aminophenyl)cyclobutanecarboxamide; 1-Amino-4-(cyclobutanecarbonylamino)benzene; p-Aminophenyl cyclobutanecarboxamide; 4-(Cyclobutanecarboxamido)aniline; (4-Aminophenyl)carbamoylcyclobutane
EINECS	Contact for details

Quality Control

Our n-(4-Aminophenyl)Cyclobutanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.