Description

2-(2-Bromophenyl)-2-(Dimethylamino)Acetonitrile is a specialized organic intermediate featuring a brominated phenyl ring and a nitrile group activated by an adjacent dimethylamino substituent. This unique molecular architecture makes it a valuable synthon for constructing complex nitrogen-containing heterocycles and pharmaceutical scaffolds. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing indole, quinoline, or other fused heterocyclic systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific bromo- and amino-functionalized aromatic cores.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate in the production of advanced organic electronic materials and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in bespoke synthesis projects.

Basic Information

Product Name	2-(2-Bromophenyl)-2-(Dimethylamino)Acetonitrile
CAS No.	299215-38-6
Molecular Formula	C10H11BrN2
Molecular Weight	239.11 g/mol
Synonyms	2-(2-Bromophenyl)-2-(dimethylamino)ethanenitrile; α-(Dimethylamino)-o-bromobenzyl cyanide; 2-Bromo-α-(dimethylamino)benzyl cyanide; (2-Bromophenyl)(dimethylamino)acetonitrile; 2-(Dimethylamino)-2-(2-bromophenyl)acetonitrile; NSC 405124; AI3-52031
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromophenyl)-2-(Dimethylamino)Acetonitrile is produced and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.