Description

N,N'-(1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[2-(Diphenylphosphino)-Benzamide is a sophisticated chiral ligand belonging to the BINAP (2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl) family, distinguished by its benzamide-modified structure. This compound matters for its exceptional ability to induce high enantioselectivity in transition metal-catalyzed asymmetric reactions, a critical factor in producing single-isomer pharmaceuticals and fine chemicals. Industrial researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors need this high-performance ligand to develop efficient and selective synthetic routes for active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C bond-forming reactions, including cross-coupling and allylic alkylation.
• Key reagent in the research and development of novel catalytic processes for the production of single-enantiomer compounds.
• Use in the synthesis of chiral ligands and catalysts with tailored steric and electronic properties.
• Application in academic and industrial R&D for exploring new asymmetric transformations.
• Potential use in the manufacture of electronic and optical materials where chiral purity is essential.

Basic Information

Item	Details
Product Name	N,N'-(1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[2-(Diphenylphosphino)-Benzamide
CAS No.	298695-62-2
Molecular Formula	C66H48N2O2P2
Molecular Weight	963.03 g/mol
Synonyms	(R)-BINAM-BINAP; (R)-N,N'-Bis(2-(diphenylphosphino)benzoyl)-1,1'-binaphthyl-2,2'-diamine; (R)-2,2'-Bis[N-[2-(diphenylphosphino)benzoyl]amino]-1,1'-binaphthyl; (R)-H8-BINAP-based Diamide Ligand; Chiral BINAP-Derived Bisphosphine Ligand; (R)-BINAM(DIPHENYLPHOSPHINO)BENZAMIDE; (1R)-N,N'-[1,1'-Binaphthalene]-2,2'-diylbis[2-(diphenylphosphino)benzamide]
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands undergoes rigorous quality testing to ensure identity, purity, and enantiomeric excess meet the stringent requirements of catalytic applications. Standard analytical techniques including HPLC, 1H/31P NMR, and chiral analysis are employed. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and spectroscopic data is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.