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Naphthalene, 2-Fluorodecahydro-, (2R,4As,8Ar)-Rel- (9Ci) CAS NO 298197-82-7


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CAS No.:298197-82-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Naphthalene, 2-Fluorodecahydro-, (2R,4As,8Ar)-Rel- (9Ci) is a stereochemically defined fluorinated decahydronaphthalene derivative, serving as a high-value synthetic intermediate and chiral building block in advanced organic synthesis. Its rigid, saturated polycyclic structure and strategically positioned fluorine atom make it a critical component for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring structure-activity relationships.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
  • Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and stereochemistry can enhance biological activity and environmental stability.
  • Ligand & Catalyst Development: Serves as a backbone for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
  • Material Science Research: Investigated as a monomer or precursor for specialty polymers and liquid crystals due to its rigid, fluorinated core structure.
  • Chemical Reference Standard: Employed as an analytical standard for method development and quality control in laboratories requiring high-purity, stereochemically pure compounds.

Basic Information

Product Name Naphthalene, 2-Fluorodecahydro-, (2R,4As,8Ar)-Rel- (9Ci)
CAS No. 298197-82-7
Molecular Formula C₁₀H₁₇F
Molecular Weight 156.24 g/mol
Synonyms rel-(2R,4aS,8aR)-2-Fluorodecahydronaphthalene; (2R,4aS,8aR)-2-Fluoro-perhydronaphthalene; 2-Fluorodecahydronaphthalene (rel-(2R,4aS,8aR)-isomer); Fluorinated Decalin Derivative; Chiral Fluorinated Naphthalene; 298197-82-7; rel-2-Fluorodecahydronaphthalene (2R,4aS,8aR)
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Quality Control

Every batch of Naphthalene, 2-Fluorodecahydro-, (2R,4As,8Ar)-Rel- (9Ci) is produced and analyzed under strict quality management systems. We employ advanced analytical techniques including chiral HPLC, GC-MS, and NMR to ensure exceptional stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain optimal stability and purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0%
Enantiomeric Purity (Chiral HPLC) ≥ 99.0% e.e.
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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