Description

Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8Ar)-Rel- (9Ci) is a fluorinated, stereochemically defined decahydronaphthalene derivative, a valuable chiral building block in advanced organic synthesis. Its rigid polycyclic framework and strategically placed fluorine atom make it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where fluorination is used to modulate bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and biological activity.
• Material Science Research: Acts as a precursor for specialty chemicals and advanced polymers requiring fluorinated, rigid molecular components.
• Asymmetric Catalysis: Employed as a ligand or a substrate in catalytic reactions to induce chirality in target molecules.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the structure-activity relationships (SAR) imparted by fluorination on polycyclic systems.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various high-tech applications.

Basic Information

Product Name	Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8Ar)-Rel- (9Ci)
CAS No.	298197-81-6
Molecular Formula	C10H15F
Molecular Weight	154.22 g/mol
Synonyms	(1R,4Ar,8Ar)-1-Fluorodecahydronaphthalene; rel-(1R,4aR,8aR)-1-Fluorodecahydronaphthalene; 1-Fluorodecahydronaphthalene (rel-(1R,4aR,8aR)-); 1-Fluoro-perhydronaphthalene (stereoisomer); Fluorinated Decalin Derivative; 1-Fluoro-cis-Decahydronaphthalene (relative configuration); CAS 298197-81-6
EINECS	Contact for details

Quality Control

Every batch of our Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8Ar)-Rel- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure high chemical purity, enantiomeric/excess, and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.