Description

Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8As)-Rel- (9Ci) is a high-purity, stereochemically defined fluorinated decalin derivative. This compound serves as a valuable and versatile fluorinated building block and chiral intermediate in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. The specific stereochemistry and fluorine substitution make it a critical reagent for structure-activity relationship (SAR) studies and the development of compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the fluorinated decalin scaffold imparts desired biological activity.
• Advanced Material Science: Serves as a precursor for specialty monomers or additives in the development of high-performance polymers with unique properties.
• Ligand and Catalyst Development: Employed as a backbone for constructing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: An important compound for academic and industrial research exploring the effects of fluorine atoms in complex, saturated ring systems.
• Reference Standard: Used as an analytical standard for quality control and method development in chromatographic analysis of complex mixtures.

Basic Information

Product Name	Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8As)-Rel- (9Ci)
CAS No.	298197-80-5
Molecular Formula	C10H17F
Molecular Weight	156.24 g/mol
Synonyms	rel-(1R,4aR,8aS)-1-Fluorodecahydronaphthalene; 1-Fluorodecahydronaphthalene, (1R,4aR,8aS)-rel-; (1R,4aR,8aS)-rel-1-Fluoroperhydronaphthalene; Fluorinated Decalin Derivative; Chiral Fluorodecalin; 1-Fluoro-cis-decalin (relative stereochemistry); Fluorodecahydronaphthalene Isomer
EINECS	Contact for details

Quality Control

Our Naphthalene, 1-Fluorodecahydro-, (1R,4Ar,8As)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.