Description

Naphthalene, 2-Fluorodecahydro-, (2R,4As,8As)-Rel- (9Ci) is a stereochemically defined fluorinated decalin derivative, serving as a sophisticated chiral building block in advanced organic synthesis. Its value lies in the precise introduction of a fluorine atom within a rigid, saturated bicyclic framework, enabling the modulation of electronic properties, metabolic stability, and conformational bias in target molecules. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, particularly in central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in constructing advanced, fluorinated active ingredients for crop protection agents, leveraging fluorine's ability to enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty fluorinated polymers and liquid crystals where the decalin structure imparts rigidity.
• Reference Standard: Provides a high-purity analytical standard for method development and quality control in laboratories synthesizing or analyzing fluorinated compounds.

Basic Information

Product Name	Naphthalene, 2-Fluorodecahydro-, (2R,4As,8As)-Rel- (9Ci)
CAS No.	298197-79-2
Molecular Formula	C10H17F
Molecular Weight	156.24 g/mol
Synonyms	rel-(2R,4aS,8aS)-2-Fluorodecahydronaphthalene; (2R,4aS,8aS)-2-Fluoro-perhydronaphthalene; 2-Fluorodecahydronaphthalene (stereoisomer); Fluorinated Decalin Derivative; Bicyclo[4.4.0]decane, 2-fluoro-, (2R,4aS,8aS)-rel-; Chiral Fluorodecalin
EINECS	Contact for details

Quality Control

Every batch of Naphthalene, 2-Fluorodecahydro-, (2R,4As,8As)-Rel- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.