Description

Naphthalene, 1-Fluorodecahydro-, (1R,4As,8Ar)-Rel- (9Ci) CAS NO 298197-78-1 is a high-purity, stereochemically defined fluorinated decalin derivative. This compound is a valuable fluorinated building block and chiral synthon, prized for its ability to introduce fluorine atoms and rigid, lipophilic decalin frameworks into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-quality intermediates for synthesis and development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorinated decalin structure can enhance biological activity, stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Acts as a fluorinated core component in the design of advanced organic electronic materials, contributing to improved charge transport and thermal stability.
• Catalyst & Ligand Development: Employed as a precursor or scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A critical reagent for academic and industrial research exploring the effects of fluorine substitution on molecular conformation and physicochemical properties.
• Flavor & Fragrance Synthesis: Potential use as an intermediate for creating complex, musky, or amber-type fragrance compounds due to its rigid polycyclic structure.

Basic Information

Product Name	Naphthalene, 1-Fluorodecahydro-, (1R,4As,8Ar)-Rel- (9Ci)
CAS No.	298197-78-1
Molecular Formula	C10H17F
Molecular Weight	156.24 g/mol
Synonyms	(1R,4aS,8aR)-1-Fluorodecahydronaphthalene; rel-(1R,4aS,8aR)-1-Fluorodecahydronaphthalene; 1-Fluorodecahydronaphthalene (stereoisomer); Fluorodecahydronaphthalene; Perfluorodecahydronaphthalene (related); F-Decalin; 1-Fluoro-cis-decalin (stereoisomer); 298197-78-1
EINECS	Contact for details

Quality Control

Our Naphthalene, 1-Fluorodecahydro-, (1R,4As,8Ar)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under an inert atmosphere (nitrogen/argon), please contact our technical team.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.