Description

Naphthalene, 2-Fluorodecahydro-, (2R,4Ar,8Ar)-Rel- (9Ci) CAS NO 298197-77-0 is a high-purity, stereochemically defined fluorinated decahydronaphthalene derivative. This compound serves as a valuable chiral building block and advanced intermediate in sophisticated organic synthesis, enabling the introduction of fluorine and a rigid polycyclic framework. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and process development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated active ingredients for crop protection products, leveraging the metabolic stability imparted by the fluorine atom.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor or a core structure for developing novel chiral ligands and catalysts in enantioselective synthesis.
• Material Science Research: Investigated as a monomer or modifying agent for creating specialty polymers with unique thermal and chemical resistance properties.
• Fluorine Chemistry Studies: Employed as a model compound in academic and industrial research to study the effects of fluorine substitution on the conformation and reactivity of polycyclic systems.
• Reference Standard: Used as an analytical standard for quality control and method development in laboratories requiring precise identification of this specific stereoisomer.

Basic Information

Product Name	Naphthalene, 2-Fluorodecahydro-, (2R,4Ar,8Ar)-Rel- (9Ci)
CAS No.	298197-77-0
Molecular Formula	C₁₀H₁₇F
Molecular Weight	156.24 g/mol
Synonyms	rel-(2R,4aR,8aR)-2-Fluorodecahydronaphthalene; (2R,4aR,8aR)-2-Fluoroperhydronaphthalene; 2-Fluoro-decahydronaphthalene, (2R,4aR,8aR)-rel-; Fluorinated Decalin Derivative; 2-Fluoro-cis-Decalin (specific isomer); Chiral Fluorodecahydronaphthalene; Fluorinated Bridged Bicyclic Compound
EINECS	Contact for details

Quality Control

Our Naphthalene, 2-Fluorodecahydro-, (2R,4Ar,8Ar)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity assessment by GC or HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.