Description

Benzyl 5-Amino-4-[(tert-Butoxycarbonyl)Amino]-5-Oxopentanoate is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of specific amino acid sequences, particularly in the synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used in academic and industrial R&D for constructing complex peptide sequences with specific side-chain protections.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces in drug delivery system development.
• Proteomics & Biochemistry: Employed in the synthesis of substrate analogs, enzyme inhibitors, and probes for studying biochemical pathways.
• Combinatorial Chemistry: A valuable building block for generating diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Benzyl 5-Amino-4-[(tert-Butoxycarbonyl)Amino]-5-Oxopentanoate
CAS No.	292870-04-3
Molecular Formula	C17H24N2O5
Molecular Weight	336.39 g/mol
Synonyms	Benzyl Nα-Boc-L-glutamine; Boc-Gln-OBzl; (S)-Benzyl 2-((tert-butoxycarbonyl)amino)-4-carbamoylbutanoate; 5-Amino-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid benzyl ester; Nα-Boc-L-glutamine benzyl ester; Boc-L-Glutamine benzyl ester; L-Glutamine, N2-[(1,1-dimethylethoxy)carbonyl]-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 5-Amino-4-[(tert-Butoxycarbonyl)Amino]-5-Oxopentanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and custom synthesis to meet specific pharmacopeial or client specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-15.0° to -18.0° (c=1 in DMF)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.