Description

7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-,(1R,4S,6R)-Rel-(9Ci) is a high-value, stereochemically defined fluorinated oxabicyclic building block. This compound is critical for introducing unique three-dimensional, fluorine-containing motifs into advanced molecular architectures, which can significantly alter physical, chemical, and biological properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and development of new drug candidates, particularly where fluorine substitution is used to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that benefit from the enhanced stability and lipophilicity imparted by the fluorinated bicyclic structure.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to construct sophisticated, chelating ligand frameworks.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research focused on exploring new fluorination methodologies and the stereoelectronic effects of fluorine.
• Fine Chemical Synthesis: Utilized in multi-step syntheses of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-,(1R,4S,6R)-Rel-(9Ci)
CAS No.	292820-76-9
Molecular Formula	C6H5F3O
Molecular Weight	150.10 g/mol
Synonyms	(1R,4S,6R)-5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene; rel-(1R,4S,6R)-5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene; 5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene (rel-(1R,4S,6R)-form); Fluorinated Oxanorbornene; Trifluorinated 7-Oxanorbornene Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and enantiomeric/excess specifications are met. A comprehensive Certificate of Analysis (COA) detailing all relevant parameters is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.