Description

2-Amino-4-(Trifluoromethyl)Phenylacetic Acid is a high-value, multi-functional aromatic amino acid derivative distinguished by its trifluoromethyl group. This compound is a critical pharmaceutical intermediate and building block for advanced organic synthesis, prized for its ability to impart unique physicochemical properties to target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with tailored properties.
• Chemical Reference Standard: Supplied to analytical laboratories for use as a high-purity standard in method development and quality control.
• Peptidomimetics: Integral for designing and synthesizing peptide analogs with improved metabolic stability and bioavailability.

Basic Information

Item	Detail
Product Name	2-Amino-4-(Trifluoromethyl)Phenylacetic Acid
CAS No.	292621-43-3
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Amino-4-(trifluoromethyl)benzeneacetic acid; α-Amino-4-(trifluoromethyl)phenylacetic acid; 4-(Trifluoromethyl)anthranilic acid acetic acid derivative; (2-Amino-4-(trifluoromethyl)phenyl)acetic acid; ATFPA; 2-Amino-α-carboxy-4-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.