Description

Benzeneacetonitrile, 2-Fluoro-α-Hydroxy-, (Alphar)- (9Ci) is a specialized fluorinated organic intermediate with significant synthetic utility. This compound matters for its role as a key chiral building block in the development of complex, high-value molecules, particularly in the pharmaceutical sector. Industries that need it include pharmaceutical R&D for active pharmaceutical ingredient (API) synthesis, agrochemical research for novel crop protection agents, and advanced material science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel, fluorinated pesticides and herbicides where the introduction of fluorine can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in advanced display technologies.
• Asymmetric Synthesis Building Block: Utilized in stereoselective reactions to construct complex molecules with defined three-dimensional structures for various fine chemical applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	Benzeneacetonitrile, 2-Fluoro-α-Hydroxy-, (Alphar)- (9Ci)
CAS No.	290374-44-6
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	(αR)-2-Fluoro-α-hydroxybenzeneacetonitrile; (R)-2-Fluoro-2-hydroxy-2-phenylacetonitrile; (R)-Mandelonitrile, 2-fluoro-; α-Hydroxy-2-fluorobenzeneacetonitrile, (R)-; 290374-44-6; (R)-(-)-2-Fluoro-α-hydroxybenzeneacetonitrile; (R)-2-Fluoro-α-hydroxybenzyl cyanide
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 2-Fluoro-α-Hydroxy-, (Alphar)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.