Description

Boc-Tyr(Tbu)-Pro-OH is a protected tripeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is essential for the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and biochemical research reagents in the pharmaceutical and biotechnology sectors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of longer, complex peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide-based drug candidates and APIs.
• Bioconjugation & Labeling: Serves as a precursor for creating labeled peptides for diagnostic and imaging applications.
• Biochemical Research: Employed in studying enzyme-substrate interactions, receptor binding, and other structure-activity relationship (SAR) studies.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Boc-Tyr(Tbu)-Pro-OH
CAS No.	289910-65-2
Molecular Formula	C₂₂H₃₂N₂O₆
Molecular Weight	420.50 g/mol
Synonyms	Boc-O-tert-butyl-L-tyrosyl-L-proline; Boc-L-Tyr(tBu)-L-Pro-OH; (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoyl]amino]pentanedioic acid; Boc-Tyr(tBu)-Pro; N-α-Boc-O-tert-butyl-L-tyrosyl-L-proline; tert-Butyloxycarbonyl-O-tert-butyl-L-tyrosyl-L-proline; Boc-Tyr(Tbu)-Pro; Boc-Tyr(O-tBu)-Pro-OH
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Tbu)-Pro-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.