Description

3-Chloro-4-Fluorophenetole is a halogenated aromatic ether compound serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure makes it a valuable intermediate for constructing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the chloro-fluoro substitution pattern contributes to biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Building block for the development of organic semiconductors and charge-transport materials.
• Functional Polymer Monomer: Intermediate for creating specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D labs.

Basic Information

Product Name	3-Chloro-4-Fluorophenetole
CAS No.	289039-45-8
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	1-Chloro-2-fluoro-4-ethoxybenzene; 4-ethoxy-2-fluoro-1-chlorobenzene; 3-Chloro-4-fluoro-1-ethoxybenzene; 2-Fluoro-4-ethoxychlorobenzene; 1-ethoxy-2-fluoro-4-chlorobenzene; Phenetole, 3-chloro-4-fluoro-; 4-ethoxychlorofluorobenzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorophenetole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.