Description

3-Bromo-5-Iodobenzonitrile is a high-purity halogenated benzonitrile derivative, a versatile and critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which enables selective cross-coupling reactions and facilitates the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, serving as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core for further functionalization via Suzuki, Stille, or Buchwald-Hartwig coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the benzonitrile moiety and halogen atoms are key structural features for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its structure can be incorporated into conjugated systems.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes, leveraging the reactivity of the iodine and bromine atoms for bioconjugation.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-5-Iodobenzonitrile
CAS No.	289039-21-0
Molecular Formula	C7H3BrIN
Molecular Weight	307.92 g/mol
Synonyms	3-Bromo-5-iodobenzonitrile; Benzonitrile, 3-bromo-5-iodo-; 5-Bromo-3-iodobenzonitrile; 3-Bromo-5-iodo-benzonitrile; 3-Bromo-5-iodobenzene carbonitrile; 289039-21-0; 3-Br-5-I-C6H3-CN
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.