Description

D-Mannose-1-C-D CAS NO 288846-86-6 is a high-purity, isotopically labeled derivative of D-mannose, a fundamental monosaccharide. This compound is critical for advanced research and development, particularly in metabolic pathway tracing and analytical method development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers requiring precise, stable isotope-labeled standards for mass spectrometry and NMR studies.

Application

• Stable Isotope-Labeled Standard for Mass Spectrometry (MS): Used as an internal standard for the accurate quantification of D-mannose and related metabolites in complex biological matrices.
• Metabolic Flux Analysis (MFA): Essential for tracing carbon pathways in glycolysis, glycan biosynthesis, and other metabolic studies in cell cultures and microorganisms.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a labeled substrate for structural and kinetic studies of enzymatic reactions involving carbohydrate metabolism.
• Pharmaceutical Research: Employed in the development and validation of bioanalytical assays for drug candidates targeting metabolic disorders or glycosylation pathways.
• Diagnostic Kit Development: Used in the formulation of calibration standards and controls for clinical diagnostic tests measuring carbohydrate metabolites.
• Biochemical Research Reagent: Acts as a specialized substrate for studying the specificity and mechanism of glycosyltransferases, kinases, and isomerases.

Basic Information

Product Name	D-Mannose-1-C-D
CAS No.	288846-86-6
Molecular Formula	C6H11DO6
Molecular Weight	181.16 g/mol (for monoisotopic)
Synonyms	1-Deuterio-D-mannose; D-[1-2H]Mannose; Mannose-1-d; (2R,3S,4S,5S)-2,3,4,5,6-Pentahydroxyhexanal-1-d; Deuterated D-Mannose (position 1); D-Mannose-1-d; [1-2H]-D-Mannopyranose
EINECS	Contact for details

Quality Control

Every batch of D-Mannose-1-C-D is produced and tested under stringent quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR and LC-MS. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profile is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.