Description

6-Fluoro-4-Methylcoumarin-3-Carbonitrile is a specialized fluorinated coumarin derivative, a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and fluorescent probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the coumarin scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for biological activity.
• Fluorescent Dye & Probe Synthesis: Serves as a core structure for developing advanced fluorescent markers and sensors used in bio-imaging and diagnostic applications.
• Organic Electronic Materials: Acts as a building block for π-conjugated systems in the research of organic light-emitting diodes (OLEDs) and other optoelectronic devices.
• Academic & Industrial R&D: Employed in methodological studies and scale-up processes for novel organic reactions and heterocyclic chemistry.
• Fine Chemical Synthesis: Used in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	6-Fluoro-4-Methylcoumarin-3-Carbonitrile
CAS No.	288399-90-6
Molecular Formula	C₁₁H₆FNO₂
Molecular Weight	203.17 g/mol
Synonyms	6-Fluoro-4-methyl-2-oxo-2H-chromene-3-carbonitrile; 6-Fluoro-4-methyl-2-oxo-2H-1-benzopyran-3-carbonitrile; 3-Cyano-6-fluoro-4-methylcoumarin; 6-Fluoro-4-methylcoumarin-3-carbonitrile; 288399-90-6; 6-Fluoro-4-methyl-2H-chromen-2-one-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Methylcoumarin-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.