Description

Oxysterol 7-α-Hydroxylase is a key enzyme involved in the bile acid biosynthesis pathway, specifically catalyzing the 7-α-hydroxylation of oxysterols. This compound is of significant interest for biochemical research and pharmaceutical development targeting metabolic disorders. It is primarily utilized by research institutions and pharmaceutical companies focused on cholesterol metabolism, liver disease, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a critical reagent in enzymatic studies to investigate the bile acid synthesis pathway and cholesterol homeostasis.
• Pharmaceutical R&D: Serves as a target or tool compound in drug discovery programs for treating cholestatic liver diseases and atherosclerosis.
• Enzyme Inhibition Studies: Employed to screen and characterize potential inhibitors that could modulate bile acid production.
• Metabolic Pathway Analysis: Essential for in vitro assays to understand the regulation and kinetics of the alternative acidic pathway of bile acid synthesis.
• Reference Standard: Used as a high-purity standard in analytical methods such as HPLC and LC-MS for quantifying enzymatic activity or metabolic products.

Basic Information

Product Name	Oxysterol 7-α-Hydroxylase
CAS No.	288309-90-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP7B1; Oxysterol 7-α-hydroxylase; Cholesterol 7-α-monooxygenase B; Cytochrome P450 7B1; SPG5A; 25-Hydroxycholesterol 7-α-hydroxylase; 7-α-Hydroxylase, Oxysterol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, activity, and stability. We adhere to GMP guidelines for research-grade biochemicals to ensure batch-to-batch consistency and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and activity. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Activity	Contact for details
Protein Content	Contact for details
Solubility	Soluble in appropriate buffers
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.