Description

2-Propyn-1-ol, 3-(2,4-difluorophenyl)-(Wx686804) is a specialized fluorinated propargyl alcohol derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive alkyne group with a difluorophenyl moiety, enabling precise chemical modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antifungal research.
• Agrochemical Synthesis: Building block for advanced crop protection agents, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science Precursor: Used in the synthesis of specialized monomers for high-performance polymers and resins.
• Chemical Biology Probes: Employed in click chemistry applications for bioconjugation and labeling due to the reactive alkyne functionality.
• Organic Synthesis Reagent: A versatile intermediate for constructing complex molecular frameworks via Sonogashira coupling and other cross-coupling reactions.

Basic Information

Product Name	2-Propyn-1-ol, 3-(2,4-difluorophenyl)-(Wx686804)
CAS No.	288100-99-2
Molecular Formula	C9H6F2O
Molecular Weight	168.14 g/mol
Synonyms	3-(2,4-Difluorophenyl)-2-propyn-1-ol; 3-(2,4-Difluorophenyl)prop-2-yn-1-ol; 2,4-Difluorophenylpropargyl alcohol; Wx686804; (2,4-Difluorophenyl)ethynylmethanol; 1-(2,4-Difluorophenyl)-2-propyn-1-ol; Propargyl alcohol, 3-(2,4-difluorophenyl)-; 288100-99-2
EINECS	Contact for details

Quality Control

Our 2-Propyn-1-ol, 3-(2,4-difluorophenyl)-(Wx686804) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.