Description

R-N,N'-Bis[[2-(Diphenylphosphino)Phenyl]Methyl]-[1,1'-Binaphthalene]-2,2'-Diamine is a sophisticated chiral ligand belonging to the privileged class of phosphine-diamine (P-N) compounds. This compound matters for its exceptional ability to induce high enantioselectivity in transition metal-catalyzed asymmetric reactions, a cornerstone of modern pharmaceutical and fine chemical synthesis. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control for creating single-enantiomer products.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral intermediates for active pharmaceutical ingredients (APIs).
• Asymmetric C-C Bond Formation: Employed in reactions like Suzuki-Miyaura cross-coupling, allylic alkylation, and hydroformylation to construct complex chiral molecules with high fidelity.
• Catalyst Screening & Development: An essential tool in high-throughput screening and the design of new chiral catalyst systems for academic and industrial R&D.
• Pharmaceutical Intermediate Synthesis: Used in the production of enantiomerically pure compounds for drug candidates targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Applied in the creation of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Material Science Research: Facilitates the synthesis of chiral polymers and ligands for advanced materials with specific optical or electronic properties.

Basic Information

Item	Detail
Product Name	R-N,N'-Bis[[2-(Diphenylphosphino)Phenyl]Methyl]-[1,1'-Binaphthalene]-2,2'-Diamine
CAS No.	288093-09-4
Molecular Formula	C66H52N2P2
Molecular Weight	935.08 g/mol
Synonyms	(R)-BINAP-Diamine; (R)-2,2'-Bis[(N-(2-(Diphenylphosphino)benzyl)amino]-1,1'-binaphthyl; (R)-[1,1'-Binaphthalene]-2,2'-diamine, N,N'-bis[2-(diphenylphosphino)phenyl]methyl]-; (R)-Bis(phosphino)diamine ligand; (R)-P-N Ligand; (R)-BINAP-DM; (R)-N,N'-Bis(o-(diphenylphosphino)benzyl)-1,1'-binaphthyl-2,2'-diamine
EINECS	Contact for details

Quality Control

Our R-N,N'-Bis[[2-(Diphenylphosphino)Phenyl]Methyl]-[1,1'-Binaphthalene]-2,2'-Diamine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC, 31P NMR, and 1H NMR, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability, consistency, and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade its catalytic performance.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
31P NMR Purity	Conforms
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.