Description

Ac-His-His-Gly-His-Oh is a synthetic peptide sequence featuring a histidine-rich motif. This compound is of significant interest in biochemical research and pharmaceutical development due to its potential metal-binding and catalytic properties derived from the imidazole side chains of the histidine residues. It is primarily utilized by researchers and manufacturers in the fields of peptide synthesis, enzymology, and as a precursor for novel therapeutic agents or diagnostic tools.

Application

• Biochemical Research: Used as a model peptide to study metal ion coordination, enzyme mimetics, and protein-protein interactions.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel therapeutics.
• Diagnostic Reagents: Potential component in the design of diagnostic assays and biosensors leveraging its specific binding characteristics.
• Catalysis Studies: Investigated for its role in artificial enzyme systems and catalytic applications due to the histidine residues.
• Peptide Library Synthesis: A building block for constructing combinatorial peptide libraries for high-throughput screening.
• Academic & Industrial R&D: Fundamental tool for universities and corporate R&D departments exploring peptide chemistry and bioinorganic applications.

Basic Information

Product Name	Ac-His-His-Gly-His-Oh
CAS No.	287399-97-7
Molecular Formula	C24H33N13O7
Molecular Weight	615.60 g/mol
Synonyms	Acetyl-His-His-Gly-His-OH; Ac-HHG-OH; N-Acetyl-L-histidyl-L-histidylglycyl-L-histidine; L-Histidine, N-acetyl-L-histidyl-L-histidylglycyl-; Histidine-rich peptide Ac-HHG; Ac-HHG-H; Ac-HHG; Ac-HHG-OH peptide
EINECS	Contact for details

Quality Control

Our Ac-His-His-Gly-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.