Description

Z-n-Et-Val-Oh is a specialized N-protected amino acid derivative, specifically a Z-protected valine ethyl ester. This compound serves as a crucial building block in organic synthesis, particularly in peptide chemistry, where it provides a protected valine residue for controlled chain elongation. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the development of active pharmaceutical ingredients (APIs) and complex peptides.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for incorporating valine.
• Pharmaceutical Research: Used in the research and development of novel peptide-based therapeutics and APIs.
• Bioconjugation: Acts as a reagent for modifying biomolecules by introducing protected amino acid functionalities.
• Chemical Biology: Employed in the synthesis of peptide probes and tools for studying biological processes.
• Custom Synthesis: Serves as a starting material or intermediate for custom organic synthesis projects in contract research and manufacturing (CRO/CMO).
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	Z-n-Et-Val-Oh
CAS No.	287208-81-5
Molecular Formula	C₁₅H₂₁NO₄
Molecular Weight	279.33 g/mol
Synonyms	N-Carbobenzoxy-L-valine ethyl ester; Z-L-Valine ethyl ester; Z-Val-OEt; Benzyloxycarbonyl-L-valine ethyl ester; N-(Benzyloxycarbonyl)-L-valine ethyl ester; (S)-Ethyl 2-((((benzyloxy)carbonyl)amino)-3-methylbutanoate; L-Valine, N-[(phenylmethoxy)carbonyl]-, ethyl ester; CBZ-L-Valine ethyl ester
EINECS	Contact for details

Quality Control

Our Z-n-Et-Val-Oh is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.