Description

Dl-Lysine-2-13C Dihydrochloride is a stable isotope-labeled derivative of the essential amino acid lysine, specifically labeled with carbon-13 at the 2-position. This compound is a critical tool for advanced research and analytical applications, providing a non-radioactive tracer for metabolic and pharmacokinetic studies. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for applications such as mass spectrometry, NMR spectroscopy, and protein/peptide research.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in in vitro and in vivo studies to investigate lysine metabolism and protein turnover.
• Quantitative Mass Spectrometry (MS): Serves as an internal standard for the accurate quantification of lysine and its metabolites in complex biological matrices via LC-MS/MS and GC-MS.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: The carbon-13 label provides a distinct signal for structural elucidation and dynamic studies of biomolecules.
• Proteomics Research: Employed in metabolic labeling strategies (e.g., SILAC - Stable Isotope Labeling by Amino acids in Cell culture) for comparative protein expression analysis.
• Pharmaceutical Development: Used in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to track the fate of drug candidates containing lysine moieties.
• Nutritional Science: Applied in research to study amino acid utilization, requirements, and bioavailability.

Basic Information

Product Name	Dl-Lysine-2-13C Dihydrochloride
CAS No.	286437-17-0
Molecular Formula	C613CH15N2O2 • 2HCl
Molecular Weight	Approx. 223.12 g/mol (for 13C1 labeled form)
Synonyms	DL-Lysine-2-13C dihydrochloride; (±)-2-Amino-6-amino-2-13C-caproic acid dihydrochloride; (RS)-2,6-Diaminohexanoic-2-13C acid dihydrochloride; Lysine-2-13C (DL) dihydrochloride; H-DL-Lys-2-13C-OH • 2HCl; 2-13C-Labeled DL-lysine dihydrochloride; (rac)-Lysine-2-13C dihydrochloride
EINECS	Contact for details

Quality Control

Our Dl-Lysine-2-13C Dihydrochloride is manufactured under controlled conditions to ensure high chemical and isotopic purity. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, chemical purity, isotopic enrichment, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.