Description

Phenacetin-Ethoxy-1-13C is a stable isotope-labeled analog of the classic analgesic compound phenacetin, where the ethoxy group is enriched with carbon-13 at the 1-position. This precise isotopic labeling is critical for applications requiring high sensitivity and specificity in analytical detection and metabolic pathway tracing. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, forensic, and analytical chemistry sectors for use as an internal standard in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for the accurate quantification of phenacetin and related compounds in complex biological matrices via LC-MS/MS and GC-MS methods.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the fate of the ethoxy moiety in vitro and in vivo.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a valuable probe in structural elucidation and mechanistic studies due to the distinct 13C signal.
• Pharmaceutical Reference Standard: Employed in the development and validation of analytical methods for drug purity and impurity profiling.
• Forensic and Toxicology Analysis: Provides a reliable standard for the detection and confirmation of phenacetin in forensic investigations.
• Isotope Dilution Analysis: Fundamental for achieving high-precision measurements in quantitative analytical chemistry.

Basic Information

Product Name	Phenacetin-Ethoxy-1-13C
CAS No.	286425-41-0
Molecular Formula	C10H1313CNO2
Molecular Weight	180.20 g/mol (for 13C1 isotopologue)
Synonyms	1-(4-Ethoxyphenyl)acetamide-ethoxy-1-13C; Phenacetin-1'-13C; N-(4-Ethoxyphenyl)acetamide-ethoxy-1-13C; Acetophenetidin-ethoxy-1-13C; 4'-Ethoxyacetanilide-ethoxy-1-13C; [1-13C]Ethoxy Phenacetin; 13C Labeled Phenacetin; Stable Isotope Labeled Phenacetin
EINECS	Contact for details

Quality Control

Our Phenacetin-Ethoxy-1-13C is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic techniques. We adhere to a rigorous quality management system to guarantee batch-to-batch consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.