Description

4-Fluorobutan-1-Amine Hydrochloride is a valuable fluorinated amine building block used in advanced organic synthesis. This compound is particularly significant for introducing the 4-fluorobutylamine moiety into target molecules, enabling the modulation of their physicochemical and biological properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, material science, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the fluorinated alkyl chain can enhance bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Bioconjugation and Probe Synthesis: Employed in the synthesis of fluorescent probes, molecular tags, and bioconjugates for diagnostic and biochemical research applications.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of advanced polymers, coatings, and specialty materials with tailored surface properties.
• Chemical Biology Research: Utilized as a tool compound to study enzyme inhibition, receptor binding, and other biological mechanisms due to its fluorine atom's unique electronic properties.

Basic Information

Product Name	4-Fluorobutan-1-Amine Hydrochloride
CAS No.	286371-70-8
Molecular Formula	C4H11ClFN
Molecular Weight	127.59 g/mol
Synonyms	4-Fluorobutylamine hydrochloride; 1-Amino-4-fluorobutane hydrochloride; 4-Fluorobutanamine hydrochloride; 4-Fluoro-1-butanamine hydrochloride; γ-Fluorobutylamine hydrochloride; (4-Fluorobutyl)ammonium chloride; 4-Fluoro-n-butylamine HCl; 286371-70-8
EINECS	Contact for details

Quality Control

Our 4-Fluorobutan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.