Description

3-[(tert-Butoxycarbonyl)Amino]-3-(3-Fluorophenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a Boc-protected amine and a fluorinated aromatic side chain. This compound is a critical pharmaceutical intermediate used in the synthesis of complex bioactive molecules, where its fluorine atom and protected functional groups enable precise structural modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and process development for therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide mimetics and small molecule drug candidates, particularly those targeting the central nervous system.
• Protease Inhibitor Development: Used in research for creating inhibitors where the 3-fluorophenyl moiety contributes to binding affinity and metabolic stability.
• Chemical Biology Probes: Serves as a precursor for fluorinated probes used to study enzyme mechanisms and protein-ligand interactions.
• Peptidomimetic Synthesis: Integral for constructing constrained peptides and peptoids with enhanced bioavailability and receptor selectivity.
• API Process Research: Employed in route scouting and optimization for the commercial-scale production of Active Pharmaceutical Ingredients (APIs).
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Item	Detail
Product Name	3-[(tert-Butoxycarbonyl)Amino]-3-(3-Fluorophenyl)Propanoic Acid
CAS No.	284493-59-0
Molecular Formula	C14H18FNO4
Molecular Weight	283.30 g/mol
Synonyms	Boc-3-(3-Fluorophenyl)-β-alanine; N-Boc-3-(3-Fluorophenyl)-β-alanine; 3-(3-Fluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid; (R/S)-3-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propanoic acid; 3-(Boc-amino)-3-(3-fluorophenyl)propionic acid; 3-(3-Fluorophenyl)-3-[(tert-butoxycarbonyl)amino]propanoic acid; β-3-Fluorophenyl-N-Boc-β-alanine
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butoxycarbonyl)Amino]-3-(3-Fluorophenyl)Propanoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are available upon request. We support development and cGMP-grade production to meet the exacting standards of pharmaceutical research and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.