Description

3-(2-Bromo-Phenyl)-3-tert-Butoxycarboxycarbonylamino-Propionic Acid is a specialized Boc-protected amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a protected amine functionality and a carboxylic acid handle, enabling precise, multi-step construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. The compound, identified by CAS number 284493-55-6, is supplied to meet the stringent demands of process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Peptidomimetics & PROTACs: Used in the construction of peptide-like molecules and proteolysis-targeting chimeras (PROTACs) due to its protected amine and versatile backbone.
• Agrochemical Synthesis: Building block for creating advanced, chiral active ingredients for crop protection products.
• Ligand & Catalyst Development: Precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
• Academic & R&D: Serves as a valuable reagent in university and institutional laboratories for methodological development in organic chemistry.

Basic Information

Product Name	3-(2-Bromo-Phenyl)-3-tert-Butoxycarboxycarbonylamino-Propionic Acid
CAS No.	284493-55-6
Molecular Formula	C15H20BrNO4
Molecular Weight	358.23 g/mol
Synonyms	3-[(2-Bromophenyl)(tert-butoxycarbonyl)amino]propanoic acid; N-Boc-3-amino-3-(2-bromophenyl)propionic acid; 3-(2-Bromophenyl)-3-[(tert-butoxycarbonyl)amino]propanoic acid; Boc-3-Amino-3-(2-bromophenyl)propionic Acid; tert-Butyl [1-(2-bromophenyl)-2-carboxyethyl]carbamate; (S/R)-3-(2-Bromophenyl)-3-(N-Boc-amino)propionic Acid; 284493-55-6
EINECS	Contact for details

Quality Control

Our production of 3-(2-Bromo-Phenyl)-3-tert-Butoxycarboxycarbonylamino-Propionic Acid adheres to a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment, offering full traceability and batch-to-batch consistency critical for your synthetic campaigns.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.