Description

3-[(tert-Butoxycarbonyl)Amino]-3-(3-Thienyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a thiophene side chain and a Boc-protected amine group. This compound matters as a critical chiral building block and intermediate for the synthesis of complex molecules, offering precise structural control for advanced research and development. It is primarily needed by pharmaceutical researchers and fine chemical manufacturers engaged in peptide mimetics, drug discovery programs, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetics & Constrained Peptides: Used to incorporate a rigid, aromatic thienyl moiety into peptide backbones, modifying bioavailability and receptor binding affinity.
• Combinatorial Chemistry & Library Synthesis: Serves as a valuable scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.
• Agrochemical Research: Employed as a building block in the synthesis of novel herbicides, fungicides, or plant growth regulators with tailored properties.
• Material Science & Organic Electronics: Potential precursor for functionalized monomers or ligands in conductive polymers or coordination complexes, leveraging the thiophene unit.
• Academic & Institutional Research: Utilized in methodological studies for asymmetric synthesis and as a standard in analytical chemistry for method development.

Basic Information

Product Name	3-[(tert-Butoxycarbonyl)Amino]-3-(3-Thienyl)Propanoic Acid
CAS No.	284492-23-5
Molecular Formula	C₁₂H₁₇NO₄S
Molecular Weight	271.33 g/mol
Synonyms	Boc-3-(3-thienyl)-β-alanine; (R/S)-3-[(tert-Butoxycarbonyl)amino]-3-(3-thienyl)propanoic acid; 3-(Boc-amino)-3-(3-thienyl)propionic acid; 3-(3-Thienyl)-3-[(tert-butoxycarbonyl)amino]propanoic acid; β-(3-Thienyl)-β-[(tert-butoxycarbonyl)amino]propionic acid; N-Boc-3-(3-thienyl)-β-alanine; DL-3-[(tert-Butoxycarbonyl)amino]-3-(3-thienyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butoxycarbonyl)Amino]-3-(3-Thienyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.