Description

3-(3-Chloro-Phenyl)-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in enabling the precise and efficient construction of complex peptide sequences, particularly those requiring the incorporation of modified or non-natural amino acids. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of amino acids, specifically for introducing the 3-(3-chlorophenyl)-alanine derivative into peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide drug candidates, including hormone analogs, enzyme inhibitors, and targeted biologics.
• Combinatorial Chemistry Libraries: Serves as a building block for creating diverse arrays of peptide compounds for high-throughput screening against biological targets.
• Bioconjugation and Probe Development: Facilitates the site-specific labeling or functionalization of peptides with fluorophores, tags, or other molecules for diagnostic and imaging applications.
• Academic & Institutional Research: Employed in biochemistry and molecular biology laboratories for studying protein-protein interactions, enzyme mechanisms, and structure-activity relationships (SAR).
• Custom Peptide Service Providers: A vital raw material for CROs and CMOs offering bespoke peptide synthesis services to the global research community.

Basic Information

Product Name	3-(3-Chloro-Phenyl)-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid
CAS No.	284492-15-5
Molecular Formula	C30H24ClNO4
Molecular Weight	497.97 g/mol
Synonyms	Fmoc-3-(3-Chlorophenyl)-β-alanine; Fmoc-3-(3-Chloro-Phenyl)-β-Ala-OH; Fmoc-3-(3-Chlorophenyl)-3-aminopropanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-chlorophenyl)-β-alanine; 3-(3-Chlorophenyl)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]propanoic Acid; Fmoc-3-Cl-β-homoPhe-OH; Fmoc-3-(3-Cl-Ph)-β-Ala-OH; Nα-Fmoc-3-(3-chlorophenyl)-β-alanine
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-Phenyl)-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid is manufactured under strict quality systems to ensure the high purity and consistency required for sensitive peptide synthesis applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.