Description

3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-3-o-Tolyl-Propionic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in providing a protected ortho-tolyl side chain, enabling the controlled construction of complex peptides with specific structural features. This high-purity intermediate is essential for research and development in pharmaceutical discovery, biotechnology, and advanced materials science, where precise molecular architecture is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptides and peptidomimetics.
• Pharmaceutical R&D: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Bioconjugation: Serves as a precursor for creating peptide-based linkers and probes for antibody-drug conjugates (ADCs) and diagnostic agents.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Material Science: A monomer for synthesizing specialized polymers and bio-inspired materials with tailored properties.
• Academic & Institutional Research: Fundamental research tool in biochemistry and organic chemistry laboratories for studying peptide structure and function.

Basic Information

Product Name	3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-3-o-Tolyl-Propionic Acid
CAS No.	284492-03-1
Molecular Formula	C25H23NO4
Molecular Weight	401.46 g/mol
Synonyms	Fmoc-3-(2-methylphenyl)-β-alanine; Fmoc-3-(o-tolyl)-β-alanine; Fmoc-3-(2-Methylphenyl)-β-Ala-OH; 3-(Fmoc-amino)-3-(2-methylphenyl)propanoic acid; 3-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(2-methylphenyl)propionic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-3-(2-methylphenyl)propanoic acid; N-Fmoc-3-(2-methylphenyl)-β-alanine
EINECS	Contact for details

Quality Control

Our 3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-3-o-Tolyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.