Description

3-(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-3-Pyridin-3-Ylpropanoic Acid is a specialized Fmoc-protected amino acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the controlled synthesis of complex peptides and peptidomimetics, particularly those incorporating the pyridin-3-yl moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used in solid-phase peptide synthesis (SPPS) to develop novel therapeutic agents and diagnostic tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of custom peptides, especially those requiring the incorporation of a pyridinylalanine analog.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide-based drug candidates, enzyme inhibitors, and receptor ligands.
• Peptidomimetic Design: Facilitates the creation of modified peptides with enhanced stability, bioavailability, or target specificity by introducing the heterocyclic pyridine ring.
• Combinatorial Chemistry Libraries: Serves as a valuable building block for generating diverse compound libraries for high-throughput screening in drug discovery.
• Bioconjugation: Can be utilized to attach peptide sequences to other molecules, surfaces, or carriers for diagnostic or targeted delivery applications.
• Academic & Institutional Research: A fundamental reagent for studies in organic chemistry, medicinal chemistry, and chemical biology focused on amino acid and peptide chemistry.

Basic Information

Product Name	3-(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-3-Pyridin-3-Ylpropanoic Acid
CAS No.	284491-95-8
Molecular Formula	C24H20N2O4
Molecular Weight	400.43 g/mol
Synonyms	Fmoc-3-(3-pyridyl)-L-alanine; Fmoc-3-(3-Pyridinyl)-L-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-pyridinyl)-L-alanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-3-yl)propanoic acid; Fmoc-Pya-OH; Fmoc-3-Pyridylalanine; Nα-Fmoc-3-(3-pyridyl)-L-alanine; Fmoc-L-3-(3-Pyridyl)alanine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and manufacturing needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch, ensuring traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under desiccant or inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.