Description

(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is a high-value chiral organophosphorus compound, serving as a sophisticated ligand and building block in advanced chemical synthesis. Its primary value lies in enabling asymmetric catalysis, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal catalysts (e.g., Rh, Pd, Ru) in enantioselective hydrogenation, cross-coupling, and hydroformylation reactions.
• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, such as certain antiviral or cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science Research: Employed in the creation of novel chiral polymers or metal-organic frameworks (MOFs) with specialized optical or catalytic properties.
• Academic & Industrial R&D: A valuable tool for method development and exploring new reaction pathways in synthetic organic chemistry laboratories.

Basic Information

Item	Detail
Product Name	(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A]
CAS No.	284472-79-3
Molecular Formula	C8H9O2P
Molecular Weight	168.13 g/mol
Synonyms	(S)-(+)-2,3-Dihydro-1,4-benzoxaphosphinine 4-oxide; (S)-(+)-3,4-Dihydro-1,4-benzoxaphosphorin 4-oxide; (S)-(+)-Dihydrobenzoxaphosphinine oxide; (S)-H8-BINAPO; (S)-2,3-Dihydrobenzo[d][1,4]oxaphosphinine 4-oxide; Chiral benzoxaphosphinine ligand; (S)-Cyclohepta[2,1-a] derivative
EINECS	Contact for details

Quality Control

Every batch of (S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is produced under strict quality management protocols to ensure high chemical and enantiomeric purity. Our standard specifications are designed to meet the rigorous demands of catalytic and synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.